Search results for " Substance-Induced"

showing 3 items of 3 documents

S-Ketamine-Induced NMDA Receptor Blockade during Natural Speech Production and Its Implications for Formal Thought Disorder in Schizophrenia: A Pharm…

2017

Structural and functional changes in the lateral temporal language areas have been related to formal thought disorder (FTD) in schizophrenia. Continuous, natural speech production activates the right lateral temporal lobe in schizophrenia, as opposed to the left in healthy subjects. Positive and negative FTD can be elicited in healthy subjects by glutamatergic NMDA blockade with ketamine. It is unclear whether the glutamate system is related to the reversed hemispheric lateralization during speaking in patients. In a double-blind, crossover, placebo-controlled study, 15 healthy, male, right-handed volunteers overtly described 7 pictures for 3 min each while BOLD signal changes were acquired…

AdultMaleSpeech productionmedicine.medical_specialtyAudiologyReceptors N-Methyl-D-AspartateBrain mappingPsychoses Substance-InducedLateralization of brain functionTemporal lobeThinking03 medical and health sciencesGlutamatergic0302 clinical medicineDouble-Blind Methodmental disordersmedicineHumansSpeechPsychiatryPharmacologyBrain MappingPsychotropic DrugsCross-Over StudiesThought disorderBrainmedicine.diseaseMagnetic Resonance Imaging030227 psychiatryOxygenPsychiatry and Mental healthSchizophreniaCerebrovascular CirculationVisual PerceptionNMDA receptorKetamineSchizophrenic PsychologyOriginal Articlemedicine.symptomPsychologyExcitatory Amino Acid Antagonists030217 neurology & neurosurgeryNeuropsychopharmacology
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Distigmine bromide induced acute psychotic disorder in a patient with multiple sclerosis.

2003

AbstractA female patient with multiple sclerosis (MS) suffered from an acute psychotic disorder after taking distigmine bromide for detrusor dysfunction. She showed a dramatic relief of her symptoms after the medication, distigmine bromide, was stopped. Distigmine is not supposed to penetrate the blood-brain barrier (BBB). However, in MS patients a leakage of the BBB could be hypothesized.

Malemedicine.medical_specialtyPsychosisMultiple Sclerosismedicine.medical_treatmentPyridinium CompoundsSuicide AttemptedBlood–brain barrierPsychoses Substance-InducedCentral nervous system diseasechemistry.chemical_compoundBromidemedicineHumansDistigminePsychiatric Status Rating ScalesChemotherapybusiness.industryMultiple sclerosisUrinary Retentionmedicine.diseasePathophysiologySurgeryPsychiatry and Mental healthmedicine.anatomical_structurechemistryParasympathomimeticsAnesthesiaFemalebusinessmedicine.drugEuropean psychiatry : the journal of the Association of European Psychiatrists
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Cannabis Use and the Risk for Psychosis and Affective Disorders.

2019

Objective: This review discusses the relationship between cannabis use and psychotic, bipolar, depressive, and anxiety disorders, as well as suicide. It summarizes epidemiological evidence from cross-sectional and long-term prospective studies and considers possible etiological mechanisms. Methods: Systematic reviews and methodologically robust studies in the field (from inception to February 2019) were identified using a comprehensive search of Medline, PsychINFO, and Embase and summarized using a narrative synthesis. Results: Consistent evidence, both from observational and experimental studies, has confirmed the important role of cannabis use in the initiation and persistence of psychoti…

early adolescencemedicine.medical_specialtyPsychosisBipolar Disorderviruses030508 substance abusePoison controlinteractionSuicide preventionPsychoses Substance-Induced03 medical and health sciences0302 clinical medicinemaniaInjury preventionCannabinoid Receptor ModulatorsmedicineHumansGenetic Predisposition to DiseaseCannabipsychosisPsychiatryDepressive Disorderbiologybusiness.industrybrain structureHuman factors and ergonomicsbiology.organism_classificationmedicine.diseaseanxietyAnxiety Disorders030227 psychiatryPsychiatry and Mental healthSuicidedepressionAnxietyMarijuana UseCannabismedicine.symptom0305 other medical sciencebusinessManiagenetic predispositionmarijuanaJournal of dual diagnosis
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